Tone, Motif and Theme in Night Essay examples -- essays research paper

When people lose their dignity, they also lose a part of the very thing that makes them human. Despair, hopelessness, fear and apathy are all ways a human can lose their humanity. The eyes provide a window onto the soul, and thus a view on the person’s mental state. The eyes also function in reverse, as a symbolic gesture of control over someone. All of this is present in Night, by Elie Wiesel, an account of human tragedy, human cruelty, human dignity, and the loss thereof.   Ã‚  Ã‚  Ã‚  Ã‚  At the start of the book, the residents of Sighet live relatively happily, oblivious to the approaching storm. Mochà © the Beadle practices the cabbala, with, â€Å"dreaming eyes† (13), living his life by his own terms. His eyes are his distinguishing factor; they show his hope for the future, his love of life, and his own freedom. Mochà ©Ã¢â‚¬â„¢s eyes seperate him from the rest of the town, elevating him to a model of self-esteem, and a confident, independent person. However, the German cruelty to the foreign Jews changes Mochà ©; â€Å"There was no longer any joy in his eyes† (17). By subjecting him to horror and fear, they removed the parts of Mochà © that made him Mochà ©. When Mochà © lost his dignity, he lost himself. The horrifying part of Mochà ©Ã¢â‚¬â„¢s experience is the Gestapo; they acted, â€Å"without passion, without haste† (16). Their apathy towards their ‘job’ turns them into monsters. The inhuman act of m urdering hundreds of people in cold blood was made even more heartless by feeling no emotion abo...

Production Cost Analysis

Production Cost Analysis: Economic Analysis as a tool for Process Development: Harvest of a High Cell-Density Fermentation For the biotech industry to be profitable, it must consider economics along with process recovery, purity, and product quality. The number of biotechnology-based human therapeutic products in the late-stage pipeline, and the average cost to commercialize a biotech product, have steadily increased. 1,2  This has required biotech companies to use economic analysis as a tool during process development and for making decisions about process design.Process development efforts now aim to create processes that are economical, as well as optimal and robust. 3-6 |[pic] | Novais et al. recently performed an economic comparison of conventional versus disposables-based technology for the production of an antibody fragment from an  E. coli  fermentation. 7The authors concluded that the capital investment required for a disposables-based option is substantially reducedâ €”less than 60% of that for a conventional option.The disposables-based running costs were 70% higher than those of the conventional equivalent. However, the net present value of the disposables-based plant was found to be positive and within 25% of that for the conventional plant. More recently, the economic feasibility of using disposables has been examined for facility design, highlighting the need to perform a thorough analysis for the application at hand. 8,9 |[pic] | |Quick Recap |Harvesting biotechnology products from cell culture or fermentation process streams is often performed by a combination of several-unit operations. Centrifugation, depth filtration, and microfiltration are commonly used. In a recent publication, different harvest approaches were investigated for a case study involving recovery of a therapeutic protein from  Pichia pastoris  fermentation broth. 10 |[pic] | |Figure 1. Schematics for options 1 and 2 | that are examined in this economic analysis | This article, the seventh in the â€Å"Elements of Biopharmaceutical Production† series, describes how economic analysis can be used to compare different processes and assist in designing an â€Å"economical† option. BACKGROUND |[pic] | |Table 1. Comparison of process performance | |for option 1 and option 2. Adapted from | |reference 10. | Figure 1 illustrates the two options that will be examined in this economic analysis.Option 1 involves a three-unit operation harvest process: centrifugation, followed by depth filtration, and completed with a concentration and buffer exchange via tangential flow ultrafiltration–diafiltration (UF–DF). Option 2 involves a two-unit operation process: microfiltration followed by a concentration and buffer exchange via tangential flow filtration (UF–DF). Table 1 presents a comparison of process performance under the two options. Under optimal conditions, both options can deliver the desired product recovery (> 80% ), harvest time (

Describe with Examples the Importance of Recognising and Responding to Concerns About Children and Young People’s Development.

U1 – 2. 210-11-11 Describe with examples the importance of recognising and responding to concerns about children and young people’s development. The following things would cause concern about a child or young person’s development. If the problem was left untreated then things could get worse, and a delay in treatment could mean that the outcome is not as good as it would have been if treatment was started earlier. 1. Speech / Language. If a child or young person does not talk to anyone or even only speaks a few words compared to others, this may cause concern. This would socially affect the child or young person’s because they would find it hard to make friends, work in groups or even interact with adults. It would also affect their communicational development because they would find it hard to speak to people and also may find it hard to listen to instructions etc. Early intervention would be the best way to respond to this concern, the first step would be to have the child or young person’s hearing checked because if they have poor hearing they will find it hard to hear people so will not want to communicate with others in case they get something wrong. . Poor reading and writing. If a child or young person has difficulties with their reading and writing it may cause concern, but this may not be noticeable until the child is around the age of 6 or 7 because by this age they should have learnt how letters are formed and start to string words together. These are the main skills a child needs to help them develop in all areas. Due to poor reading and writing the child or young person will start to fall behind his peers of the same age. They may find it difficult to interact or make friends with others who are more advanced than them, in case they are bullied etc. They would struggle with their intellectual development not only with the reading and writing, but they would struggle with their memory and even their concentration. They would have a low self-esteem, and could also have a speech problem. They may become very disruptive in the class, because they can not do the work etc. The best way to respond to this concern would to inform the main teacher and also inform the SENCO, so that they can follow it up correctly as the child or young person may have dyslexia. 3. CO-Ordination. If a child or young person starts to show signs of clumsiness or struggle with their fine motor or gross motor movements then this would cause concern and make you wonder what could be causing this? Their social development may be affected as they may find it hard to interact with other children when playing games in the playground. The child or young person will have problems with fine motor and gross motor skills and therefore may struggle to use a pen/pencil, have hand-eye co-ordination problems, balance and even running. This will also have a knock on affect on them intellectually, because if they are unable to hold a pen/pencil then they will be unable to write. The best way to respond to this concern would yet again inform the child’s teacher and also inform the SENCO, as the child or young person may suffer from dyspraxia, and they will need to be assessed. . Signs of Abuse. It can be very difficult to recognise signs of abuse in a child or young person. They are some signs, which could alert staff to the fact that the child or young person might be being abused at home, for example constant bruising, or having unusual injuries for the child or young person. This may have an affect on their emotional development because they may suffer from low self-esteem, and be unable to name the emotion they ar e feeling. They may also have problems with their physical development because if the child or young person has been physically abused and hurt then they may be in pain when doing things. The best way to respond to this kind of concern is to inform the child’s teacher and also the head teacher and then they can then inform social services and the police and then they can look into the situation more closely. 5. Diet / Weight. If a child or young person’s diet / weight were to suddenly drop or increase in a short period of time then this would cause some concern about them. Things that would raise concern would be if they came to school and did not have any lunch (packed lunch) or if they only eat small amounts, this would make the child very irritable and very lethargic because they are not getting the right nourishment for one reason or another. If the child or young person is malnutrition they may have difficulty with their social development because they nay struggle with their speech and therefore are unable to interact and make friends. Their physical development may develop at a slower rate compared to the other children etc. The signs of a child being under weight could be that they have an illness like leukaemia, or the fact that they are being neglected at home. The best way for staff to approach this would to be speech to the parents/carer of the child or go to social services. 6. Behaviour. If a child or young person’s behaviour is more along a negative line constantly then this may cause concern and make staff etc wonder what could be causing the constant negative behaviour. This behaviour could be signs that the child or young person has ADHD, Autism etc. If left untreated then the child or young person’s development would be affected in a big way. Socially no one would want to be their friend if they constantly hit, kick or even bite others, this would then make is hard for them to make friends and share with others. If the child does have a condition that is affect their behaviour this would cause them to have poor concentration and their listening skills would also suffer. Emotionally they may be constantly angry or confused by what is going on. The best way to respond to this would be to inform SENCO and maybe introduce a behaviour chart in the class and reward the good behaviour.

Drover’s Wife Reflection Essay

The Drover’s Wife, whose writer is Henry Lawson, portrays a bushwoman who was left to live in a small house with four children and one snake-dog while her husband was away droving. One day, when a snake entered the house, her house-dog, her son, Tommy, and she tried to kill it, but it disappeared into the cracks. While sitting, sewing and watching for the snake all night, she thought of her past hard times such as droughts, floods, bulls, drunken man and swagman. Finally, when dawn approached, the snake came out; it was killed and burnt. The drover’s wife is the character whom I am interested in the most due to a few reasons. Firstly, she is a responsible wife and a protective mother; for instance, to maintain the properties her husband had earned for years, she struggled to dig an overflow gutter in a rainstorm, which was too hard for a woman. Also, she protected her children from danger by spending all night guarding them carefully. Lastly, she is brave; despite risks, she went into the flames just to save her baby. I think if other people face this situation, they might do nothing besides weeping. After reading this story, I have gained an important experience which is that woman, herself, has to be independent and responsible because living in society is complicated as she might encounter many difficulties and cannot always depend on other people or men. As can be seen, although the bonny drover’s wife was left with four children and had to deal with the hardships of life, she independently strived to protect herself and children and overcame each challenge. Although the story is short, it has captured almost all my attention and has provided many useful tips for livings; thus, I would strongly encourage my friends to read it in order to let them perceive the precious experiences and develop their personal growth.

Homework Essay Example | Topics and Well Written Essays - 500 words - 9

Homework - Essay Example The western wing on the other hand contains the stairwell and smoke tower. The base of the building has intertwined truss system that helps in enhancing the stability of the entire structure in case of any earthquake. The building also has an X-bracing on the top, which assists in resisting torsion movement about the vertical axis of the building (Irvine). The construction process of the Transamerica Pyramid involved the use of various materials deemed as of great quality. Before lying of the first material, the point where the building stands was excavated to a depth of 52 feet. The bottom of the building has complicated system of steel rod reinforcements exceeding 300 miles thickness. About 16000 cubic yards of solid concrete covers the system of the reinforced steel rods. The entire base concrete of the Transamerica Pyramid is in such a way that the entire building moves in case of earthquake. The movement helps in distributing the shockwaves thus reducing damages (EMPROIS). The external parts of the Transamerica Pyramid are fixed with aggregates of quartz that form panels. There are also some rods designed to reinforce the panels at four points on every floor. There is also systematic spacing of the panels that helps in ensuring lateral movement of the building in case of earthquake or tremor. The panels comprises of aluminum louvered structures. The louvered aluminum panels projects to the top to form a 64 meters high spire (EMPROIS). The 48th floor of the building has conference room that provides 360-degree aerial view of the city. The entire external part of the building is white in color. I am always attracted to Transamerica Pyramid because of numerous features the building exhibits. First, I have found it fantastic to explore how the fifth floor of the building happen to be the largest floor and not the first or the second. Logically thinking and considering the shape of the building, the largest floor ought to

Research Reports Paper Example | Topics and Well Written Essays - 500 words

Reports - Research Paper Example In other words, the research report chosen substantially conforms to the standard template or outline presented in the text (Trieschmann, Dennis, Northcraft and Niemi, 2000, pp. 1130-1141). To be specific, the chosen research report details an Abstract, an Introduction, a section on Methods, a Results section, and a Discussion section. The Conclusion is lumped together with the Discussion, and forms the last part of that section, and ties with the first paragraph of the Discussion section too. The first paragraph looks at the factors that impact MBA program performance and research performance, and they are different, with also differing performance ratings for each set of criteria for all of the business schools examined. Meanwhile, the other half of that Conclusion found in the first paragraph of the Discussion section is in the last paragraph, and details a recommendation for business schools to be more balanced in their emphasis on both MBA program performance and business research performance. In this sense, based on the Discussion above, this research report deviates somewhat from the standard outline in the text, in that there is no separate Conclusion section. Other than that, the research report substantially complies with all of the required sections in the template (Trieschmann, Dennis, Northcraft and Niemi, 2000, pp. 1130-1141). To further discuss, the research report details a Discussion section that substantially tackles research implications, limitations, and directions/suggestions for future research, though not in the ordering as specified in the text outline. As already mentioned above, the Conclusion can be found as consisting of the first and last paragraphs of the section. Meanwhile, directions for future research are found right in the middle of the section, around the fifth and sixth paragraphs out of nine paragraphs, whereas in the text outline Future